Assuntos
Angioedemas Hereditários/tratamento farmacológico , Terapia por Infusões no Domicílio/efeitos adversos , Terapia por Infusões no Domicílio/métodos , Peptídeos/efeitos adversos , Peptídeos/uso terapêutico , Adulto , Angioedemas Hereditários/enfermagem , Feminino , Terapia por Infusões no Domicílio/enfermagem , Humanos , Calicreínas/antagonistas & inibidores , Masculino , Estudos RetrospectivosRESUMO
Hereditary angioedema is characterised by unpredictable, painful and potentially life-threatening oedema. Recently, some C1 inhibitors have been approved for self-administration and/or routine prevention, enabling patients to be proactive in managing their disease and reducing the burden of illness. This article discusses the effect of these advances from a specialist nurse's perspective.
Assuntos
Angioedemas Hereditários/enfermagem , Angioedemas Hereditários/tratamento farmacológico , Angioedemas Hereditários/genética , Proteína Inibidora do Complemento C1/administração & dosagem , Proteína Inibidora do Complemento C1/uso terapêutico , Medicina Baseada em Evidências , Humanos , Infusões Intravenosas , Papel do Profissional de Enfermagem , Autoadministração , Reino UnidoRESUMO
At an international hereditary angioedema (HAE) expert meeting, results from a survey were used to guide discussion on how best to advise patients on self-administering intravenous C1 esterase inhibitor therapy. Treatment differences across Europe were highlighted, together with the practicalities of self-administration and useful resources for patients in the future. The international HAE experts noted an increase in the uptake of self-administration, with patients being trained by nursing staff. All patients who are willing and able to self-administer should be offered this treatment option and patients should be encouraged to treat attacks early. Several initiatives were suggested regarding support for patients who self-administer therapy, including a 24-hour helpline and home care agencies.
